CD4 antibody (GK1.5)

CD4 antibody (GK1.5)
Artikelnummer
GTX44529-500
Verpackungseinheit
500 μg
Hersteller
GeneTex

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Clone Name: GK1.5

Light Chain: Kappa

Product Description: The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

Calculated MW: 51

Form: Liquid

Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.

Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Uniprot ID: P06332

Antigen Species: Mouse

Immunogen: Murine CD4.

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: CD4 antigen
Mehr Informationen
Artikelnummer GTX44529-500
Hersteller GeneTex
Hersteller Artikelnummer GTX44529-500
Green Labware Nein
Verpackungseinheit 500 μg
Mengeneinheit STK
Reaktivität Mouse (Murine), Hamster, Syrian Golden Hamster
Klonalität Monoclonal
Methode Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Western Blotting, Neutralization, Immunocytochemistry, Inhibition Assay, Fluorescence-Activated Cell Sorting (FACS)
Isotyp IgG2b
Human Gene ID 12504
Wirt Rat
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