CD40, Mouse(FGK45.5), 1mg/mL

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Description: Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Rattus norvegicus (laboratory rat),

Clone: FGK45.5

Entrez Gene ID: 21939

Immunogen: Purified recombinant Mouse CD40 fusion protein

Expected AB Applications: Flow, surface (published for clone)/Functional studies (published for clone)

Z-Antibody Applications: Flow, surface (published)/Functional studies (published)

• Artikelnummer: BTMBNUM2005-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2005-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Flow Cytometry, Functional Studies
• Isotyp: IgG2a kappa
• Wirt: Rat
• Konjugat: Unconjugated