CD43 (T-Cell Marker) (rSPN/839), 1mg/mL

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Description: This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 . Epitope of MAb Bra7G is clearly different from that of MAb rSPN/839, called "b" as opposed to "a" for rSPN/839. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: rSPN/839

Entrez Gene ID: 6693

Immunogen: Recombinant full-length human CD43 protein

Verified AB Applications: Flow (verified)/IF (verified)/IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: Flow (verified)/IF (verified)/IHC, FFPE (verified)/WB (verified)

• Artikelnummer: BTMBNUM2220-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2220-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry
• Isotyp: IgG1
• Wirt: Mouse
• Konjugat: Unconjugated