CD45RO

CD45RO, Monoclonal, IgG2a, Host: Mouse, FITC

Clone: UCHL1.

Conjugate: FITC.

Immunogen: Human IL-2-dependent T-cell line.

Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).

Recommended Usage: CD45RO, clone UCHL1 is a mAb intended for identification/enumeration of CD45RO present on approx. 40% of peripheral blood T lymph using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

The CD45RO antigen is present at low density early in the T-lymphocyte maturation cycle. Upon activation by phytohemagglutinin (PHA) or alloantigen, naive T lymphocytes first acquire CD45RO and then lose CD45RA. When these activated T lymphocytes are rechallenged, the cells that exhibit a secondary response are primarily CD45RO+ , leading to the concept that CD45RO + cells are a primed population of memory T lymphocytes.

• Artikelnummer: IMS45ROF-100T
• Hersteller: Immunostep
• Hersteller Artikelnummer: 45ROF-100T
• Verpackungseinheit: 100 Tests
• Mengeneinheit: PAK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG2a
• Human Gene ID: 5788
• Wirt: Mouse
• Konjugat: Conjugated, FITC