CD54 / ICAM-1(15.2), 1mg/mL

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Description: Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: 15,2

Entrez Gene ID: 3383

Immunogen: Human monocytes.

Expected AB Applications: IHC (frozen) (published for clone)/Flow, surface (published for clone)/Functional studies (published for clone)/IF (published for clone)

Z-Antibody Applications: Flow, surface (published)/Functional studies (published)/IF (published)/IHC, frozen (published)

• Artikelnummer: BTMBNUM2853-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM2853-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Pig (Porcine)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Flow Cytometry, Functional Studies
• Isotyp: IgG1 kappa
• Wirt: Mouse
• Konjugat: Unconjugated