Clone Name: 12-140-10
Application Note: IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 77
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Uniprot ID: P06731
Antigen Species: Human
Immunogen: CEA isolated from liver metastasis of colorectal carcinomas by PCA extraction followed by ion exchange and gel filtration chromatography.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: carcinoembryonic antigen related cell adhesion molecule 5