CD8 alpha antibody (53-6.7)

Clone Name: 53-6.7

Light Chain: Kappa

Product Description: The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Calculated MW: 27

Form: Liquid

Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.

Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Uniprot ID: P01731

Antigen Species: Mouse

Immunogen: Mouse spleen cells

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: CD8 antigen, alpha chain

• Artikelnummer: GTX00604-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX00604-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Immunocytochemistry, Fluorescence-Activated Cell Sorting (FACS)
• Isotyp: IgG2a
• Human Gene ID: 12525
• Wirt: Rat