CD9

CD9, Monoclonal, IgG2a, Host: Mouse, FITC

Clone: VJ1/20.

Conjugate: FITC.

Immunogen: Tissue / cell preparation (Human tonsil).

Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).

Recommended Usage: CD9, clone VJ1/20, is a mAb intended for the identification/ enumeration of human platelets using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

Description: This antibody reacts with the CD9-antigen, which is expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. In pre-B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41/CD61 (GPIIb/GPIIIa).

CD9 is a 24 kD type III transmembrane protein also known as tetraspanin, MRP-1 and DRAP-24. It is a member of the tetraspan family (spanning the membrane four times) found on platelets, B cell progenitors, activated lymphocytes, granulocytes, endothelial cells and epithelial cells. CD9 induces adhesion, platelet aggregation, and B cell development. CD9 has been shown to associate with CD63, CD81, CD82, and CD36 and to bind to β1 integrins.

• Artikelnummer: IMS9F-100T
• Hersteller: Immunostep
• Hersteller Artikelnummer: 9F-100T
• Green Labware: Nein
• Verpackungseinheit: 100 Tests
• Mengeneinheit: PAK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: IgG2a
• Human Gene ID: 928
• Wirt: Mouse