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Encompassing Amino Acids: CDK14: 1-469(end))Cyclin Y: 2-341(end)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: CDK14/Cyclin Y complex of human CD14, also known as PCTK1, CDK16, and PCTAIRE1 GenBank Accession No. NM_012395, a.a. 1-469(end) with N-terminal GST-tag, MW=72 kDa, and human Cyclin Y, also known as CCNY, CBCP1, CCNX, and CFP1, GenBank Accession No. NM_145012, a.a. 2-341(end) with N-terminal GST-tag. MW= 64 kDa. Co-expressed in a Baculovirus infected Sf9 cell expression system.
Formulation: 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 10 mM glutathione, 0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Genbank: CDK14: NM_012395; Cyclin Y: NM_145012
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Tags: CDK14: N-terminal GST-tagCyclin Y: N-terminal GST-tag
Uniprot: CDK14: O94921Cyclin Y: Q8ND76
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Yang, T. et.al, Gene 267: 165-172, 2001.
2. Gao, Y. et.al, Cell Res. 16: 539-547, 2006.