Application Note: WB: 1:1000-1:3000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 37
Form: Liquid
Buffer (with preservative): PBS pH 7.4, 150 mM NaCl, 50% glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
Uniprot ID: P40199
Antigen Species: Human
Immunogen: A synthesized peptide derived from human CEACAM6(Accession P40199), corresponding to amino acid residues P220-S270.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: carcinoembryonic antigen related cell adhesion molecule 6