Claudin 18.2 antibody (ARC5062-02)

Clone Name: ARC5062-02

Application Note: IHC-P: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 28

Form: Liquid

Buffer (with preservative): PBS pH 7.3, 0.05% BSA, 50% glycerol, 0.05% proclin300.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]

Uniprot ID: P56856

Antigen Species: Human

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CLDN18.2 (P56856-2).

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: claudin 18

• Artikelnummer: GTX04575-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04575-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 51208
• Wirt: Rabbit