CLEC9A / DNGR1 (Dendritic Cell Marker)(8F9), 1mg/mL

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Description: This MAb recognizes a protein of 27 kDa, identified as CLEC9A (C-type lectin domain family 9 member A). Its epitopes maps in aa 50-110. The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A, also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin- like receptor (CTLR) that acts as an activation receptor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: 8F9

Entrez Gene ID: 283420

Immunogen: RBL-2H3 cells expressing human DNGR-1 fused to an HA epitope

Expected AB Applications: Flow, surface (published for clone)/IF (published for clone)

Z-Antibody Applications: Flow, surface (published)/IF (published)

• Artikelnummer: BTMBNUM3063-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM3063-50
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Flow Cytometry
• Isotyp: IgG2a kappa
• Wirt: Mouse
• Konjugat: Unconjugated