Cortactin Polyclonal Antibody, Rabbit

Cortactin Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92678-60
Verpackungseinheit
60 µl
Hersteller
Elabscience Biotechnology

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Abbreviation: Cortactin

Target Synonym: CTTN;EMS1;cortactin

Conjugation: Unconjugated

UNIProt ID: Q14247

Background: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human Cortactin

Dilution: WB 1:500-1:2000,IF 1:50-1:200
Mehr Informationen
Artikelnummer ELSE-AB-92678-60
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer ELA-E-AB-92678-60
Green Labware Nein
Verpackungseinheit 60 µl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Polyclonal
Methode Immunofluorescence, Western Blotting
Isotyp IgG
Wirt Rabbit
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