Cyclobenzaprine-d6 (hydrochloride), CAS 2748492-38-6

Formulation: A solid

Formal Name: 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-d3-1-propanamine, monohydrochloride

Purity: ≥99% deuterated forms (d1-d6)

Formula Markup: C20H15D6N • HCl

Formula Weight: 317,9

Shelf life (days): 1460

CAS Number: 2748492-38-6

Notes: Cyclobenzaprine-d6 is intended for use as an internal standard for the quantification of cyclobenzaprine by GC- or LC-MS. Cyclobenzaprine is a skeletal muscle relaxant.{25917,25918,25919} It is an antagonist of M1, M2, and M3 muscarinic acetylcholine receptors (mAChRs; Kis = 25, 60, and 6 nM, respectively), the histamine H1 receptor (IC50 = 20 nM), and serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2B, and 5-HT2C (Kis = 1,685, 330, and 56 nM, respectively). Cyclobenzaprine (1 mg/kg) prevents increases in the flexor reflex induced by the 5-HT2 receptor agonist DOI in spinalized rats.{25919} Formulations containing cyclobenzaprine have been used as muscle relaxants.

• Artikelnummer: CAY39834-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39834-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung