Product Type: Inhibitor
CAS No.: 302962-49-8
MolecularFormula: C22H26ClN7O2S
Molecular Weight: 488
Source: Synthetic
Purity: ≥98%
Solubility: Soluble in DMSO (200 mg/ml), ethanol (very poorly ), and water (very poorly )
Appearance: Crystalline solid
PubChem CID: 3062316
Scientific Background: Dasatinib is a dual Src and Abl kinase inhibitor with ∼325 times more potency against BCR-ABL than imatinib. Specifically, it inhibits autophosphorylation and substrate phosphorylation in a concentration-dependent manner.
References: 1. Benjamini O., et al. (2014) Am. J. Hematology. 89(3): 282–287.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.