Scientific Background: A potent, selective and reversible inhibitor of the AAA-ATP p97 (ATPase associated with diverse cellular activities). Ki=3.2 M. It blocks ubiquitin-dependent protein clearance pathways. Cell permeable.
References: 1. Chou T.F., et al. 2011 PNAS 108:4834.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.