DLK1, Avi-His-Tag HiP™ Recombinant

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Background: Delta like non-canonical Notch ligand 1 (DLK1), also known as Protein delta homolog 1, is a cleavable single-pass transmembrane protein with a restrict pattern of expression (neuroendocrine tissues and progenitor cells). It plays a role in neuroendocrine differentiation and regulates adipose tissue homeostasis. Low levels of the protein are associated with acromegaly. Overexpression of DLK1 is observed in endocrine-related cancers, such as ovarian and adrenocortical cancer, and associated with a poor prognosis. It is considered a promising therapeutic target for such malignancies. 

Description: Delta like non-canonical Notch ligand 1 (DLK1), encompassing amino acids 24-303. This construct contains a C-terminal Avi-tag™ followed by a His-tag (6xHis). The recombinant protein was affinity . HiP™ indicates a high purity protein (≥90% pure) and less than 10% aggregation as measured by gel filtration.

Format: Aqueous buffer solution.

Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Genbank: NM_003836.6

Host Cell Line: HEK293

Purity: ≥90%

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Avi-Tag™, His-Tag

Uniprot: P80370

Warnings: Avoid freeze/thaw cycles

Biosafety Level: Not applicable (BSL-1)

• Artikelnummer: BPS101745-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 101745-1
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK
• Wirt: Human