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DLK1, Avi-Tag, His-Tag, Biotin-Label Recombinant
DLK1, Avi-Tag, His-Tag, Biotin-Label Recombinant
Artikelnummer
BPS101781-1
Verpackungseinheit
25 µg
Hersteller
BPS Bioscience
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Background: Delta like non-canonical Notch ligand 1 (DLK1), also known as Protein delta homolog 1, is a cleavable single-pass transmembrane protein with a restricted pattern of expression (neuroendocrine tissues and progenitor cells). It plays a role in neuroendocrine differentiation and regulates adipose tissue homeostasis. Low levels of the protein are associated with acromegaly. Overexpression of DLK1 is observed in endocrine-related cancers, such as ovarian and adrenocortical cancer, and associated with a poor prognosis. It is considered a promising therapeutic target for such malignancies.
Description: Delta like non-canonical Notch ligand 1 (DLK1), encompassing amino acids 24-303. This construct contains a C-terminal Avi-tag™ followed by a His-tag (6xHis). The recombinant protein was affinity purified. This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation confirmed to be ≥90%.
Format: Aqueous buffer solution.
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Genbank: NM_003836.6
Host Cell Line: HEK293
Purity: ≥90%
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Avi-Tag™, His-Tag
Uniprot: P80370
Warnings: Avoid freeze/thaw cycles
Biosafety Level: Not applicable (BSL-1)
Background: Delta like non-canonical Notch ligand 1 (DLK1), also known as Protein delta homolog 1, is a cleavable single-pass transmembrane protein with a restricted pattern of expression (neuroendocrine tissues and progenitor cells). It plays a role in neuroendocrine differentiation and regulates adipose tissue homeostasis. Low levels of the protein are associated with acromegaly. Overexpression of DLK1 is observed in endocrine-related cancers, such as ovarian and adrenocortical cancer, and associated with a poor prognosis. It is considered a promising therapeutic target for such malignancies.
Description: Delta like non-canonical Notch ligand 1 (DLK1), encompassing amino acids 24-303. This construct contains a C-terminal Avi-tag™ followed by a His-tag (6xHis). The recombinant protein was affinity purified. This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation confirmed to be ≥90%.
Format: Aqueous buffer solution.
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Genbank: NM_003836.6
Host Cell Line: HEK293
Purity: ≥90%
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Avi-Tag™, His-Tag
Uniprot: P80370
Warnings: Avoid freeze/thaw cycles
Biosafety Level: Not applicable (BSL-1)
| Artikelnummer | BPS101781-1 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 101781-1 |
| Green Labware | Nein |
| Verpackungseinheit | 25 µg |
| Mengeneinheit | STK |
| Wirt | Human |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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