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DMP1 antibody
DMP1 antibody
Artikelnummer
GTX04077-100
Verpackungseinheit
100 μl
Hersteller
GeneTex
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Application Note: WB: 1:1000-1:3000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 56
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: Q13316
Antigen Species: Human
Immunogen: A synthesized peptide derived from human DMP1(Accession Q13316), corresponding to amino acid residues S488-Y513.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: dentin matrix acidic phosphoprotein 1
Calculated MW: 56
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: Q13316
Antigen Species: Human
Immunogen: A synthesized peptide derived from human DMP1(Accession Q13316), corresponding to amino acid residues S488-Y513.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: dentin matrix acidic phosphoprotein 1
| Artikelnummer | GTX04077-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX04077-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus), Monkey (Primate) |
| Klonalität | Polyclonal |
| Methode | Immunohistochemistry (paraffin), Western Blotting |
| Isotyp | IgG |
| Human Gene ID | 1758 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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