Product Type: Inhibitor
CAS No.: 137206-97-4
MolecularFormula: C16H16ClN2O2
Molecular Weight: 339,2
Source: Synthetic
Purity: ≥98% (HPLC)
Solubility: Soluble to 100 mM in water
Appearance: White to beige solid
PubChem CID: 45073427
Scientific Background: DMPQ dihydrochloride is a potent and selective inhibitor of human vascular β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ). It displays > 100-fold selectivity over EGFR tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C.
References: 1. Dolle R.E., et al. (1994) J. Med. Chem. 37(17): 2627–2629.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.