Dopamine beta Hydroxylase antibody (HL1163)

Clone Name: HL1163

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 69

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017]

Uniprot ID: P09172

Antigen Species: Human

Immunogen: Recombinant protein encompassing a sequence within the center region of human Dopamine beta Hydroxylase. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: dopamine beta-hydroxylase

• Artikelnummer: GTX636467-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX636467-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 1621
• Wirt: Rabbit