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Dystrophin antibody (Dy4/6D3)
Dystrophin antibody (Dy4/6D3)
Artikelnummer
GTX01871-500
Verpackungseinheit
500 μl
Hersteller
GeneTex
Verfügbarkeit:
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Clone Name: Dy4/6D3
Application Note: IHC-Fr: 1:20. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 427
Specificity/Sensitivity: This antibody reacts strongly with the rod domain (between amino acids 1181 and 1388) of human dystrophin. No reactivity with mdx mouse tissue of DMD/BMD patients who have a gene deletion which removes the antibody binding site.,We do not recommend use of this product for Chicken.
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Uniprot ID: P11532
Antigen Species: Human
Immunogen: Bacterial fusion protein (Hoffman EP et al., 1987).
Purification: Unpurified
Conjugation: Unconjugated
Full Name: dystrophin
Application Note: IHC-Fr: 1:20. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 427
Specificity/Sensitivity: This antibody reacts strongly with the rod domain (between amino acids 1181 and 1388) of human dystrophin. No reactivity with mdx mouse tissue of DMD/BMD patients who have a gene deletion which removes the antibody binding site.,We do not recommend use of this product for Chicken.
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Uniprot ID: P11532
Antigen Species: Human
Immunogen: Bacterial fusion protein (Hoffman EP et al., 1987).
Purification: Unpurified
Conjugation: Unconjugated
Full Name: dystrophin
| Artikelnummer | GTX01871-500 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX01871-500 |
| Green Labware | Nein |
| Verpackungseinheit | 500 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Rabbit, Dog (Canine), Hamster |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (frozen) |
| Isotyp | IgG2a |
| Human Gene ID | 1756 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
