EndoPDI Antibody, Clone 2E7/7

Mouse Anti-Human EndoPDI Monoclonal IgG2a

Target: PDI

Conjugate: Unconjugated

Product Type: Monoclonal

Clone Number: 2E7/7

Immunogen: Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the Human EndoPDI protein

Swiss-Prot: Q8NBS9

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~48kDa.

Cellular Localization: Endoplasmic Reticulum,Endoplasmic Reticulum Lumen

Scientific Background: Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia (1).

References: 1. Sullivan D.C., et al. (2003) J Biol Chem. 278 (47) 47079-47088.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-204D
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-204D
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, ELISA, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2a
• Human Gene ID: 81567
• Wirt: Mouse