EpCAM antibody (MOC-31)

Clone Name: MOC-31

Light Chain: Kappa

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 35

Positive Control: Colon carcinoma

Specificity/Sensitivity: This antibody reacts with a transmembrane glycoprotein present on most glandular epithelium and tumors originating from such epithelium. This antibody has been used to distinguish adenocarcinoma from mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Form: Liquid

Buffer (with preservative): Tissue culture supernatant diluted in Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.

Concentration:

Background: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Uniprot ID: P16422

Antigen Species: Human

Immunogen: Neuraminidase treated human cells from a variant small cell lung carcinoma cell line

Purification: unpurified

Conjugation: Unconjugated

Full Name: epithelial cell adhesion molecule

• Artikelnummer: GTX01685-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX01685-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Human Gene ID: 4072
• Wirt: Mouse