Estrogen Receptor alpha antibody (SC1)

Clone Name: SC1

Application Note: WB: 1-5 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 66

Positive Control: MCF-7

Specificity/Sensitivity: This antibody is specific for ER alpha protein, and it does not cross react with ER beta protein.

Form: Liquid

Buffer (with preservative): PBS, 50% Glycerol, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

Uniprot ID: P03372

Antigen Species: Human

Immunogen: Recombinant human protein expressed in mammalian cells

Purification: Purified by protein A

Conjugation: Unconjugated

Full Name: estrogen receptor 1

• Artikelnummer: GTX02805-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02805-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 2099
• Wirt: Mouse