Conjugation: HRP: Horseradish Peroxidase
Description of Target: ETFB is the electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. This gene encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene.
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ETFB
Key Reference: Schiff,M., (2006) Mol. Genet. Metab. 88 (2), 153-158
Molecular Weight: 28kDa
Peptide Sequence: Synthetic peptide located within the following region:
TADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Electron transfer flavoprotein subunit beta
Protein Size: 255
Purification: Affinity Purified
Subunit: beta