Product Type: Inducer
CAS No.: 33419-42-0
MolecularFormula: C29H32O13
Molecular Weight: 588,56
Source: Synthetic
Purity: >98%
Solubility: Soluble to 100 mM in DMSO
Appearance: White solid
PubChem CID: 36462
Scientific Background: Etoposide inhibits the enzyme topoisomerase II, which unwinds DNA, and be doing so causes the DNA strand to break. Cancer cells are then less likely to be able to repair this damage (1).
References: 1. Gordaliza M., et al. (2004) Toxicon. 44(4): 441-459.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.