EX-527, CAS 49843-98-3

SIRT1 inhibitor

Product Type: Inhibitor

CAS No.: 49843-98-3

MolecularFormula: C13H13ClN2O

Molecular Weight: 248,7

Source: Synthetic

Purity: >98% (TLC), NMR conforms

Solubility: Soluble in 18 mg/ml DMSO or 10 mg/ml Ethanol

Appearance: Light Yellow Solid

PubChem CID: 5113032

Scientific Background: Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable.

References: 1. Solomon J.M., et al., (2006) Mol. Cell. Biol. 26: 28.2. Anderson J.L., et al., (2011) Mol.Cell 43: 834.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-353-5MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-353-5MG
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK