FANCD2 antibody (GT1223)

Clone Name: GT1223

Application Note: WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 164

Form: Liquid

Buffer (with preservative): PBS, 50% Glycerol, 0.02% Sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Uniprot ID: Q9BXW9

Antigen Species: Human

Immunogen: A synthesized peptide derived from human FANCD2.

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: FA complementation group D2

• Artikelnummer: GTX01531-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX01531-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Recombinant
• Methode: Western Blotting
• Isotyp: IgG
• Human Gene ID: 2177
• Wirt: Rabbit