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Fascin 1 antibody (IM20)
Fascin 1 antibody (IM20)
Artikelnummer
GTX01968-500
Verpackungseinheit
500 μl
Hersteller
GeneTex
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Clone Name: IM20
Light Chain: Kappa
Application Note: WB: 1:100–1:200. IHC-P: 1:200–1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 55
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Uniprot ID: Q16658
Antigen Species: Human
Immunogen: Prokaryotic recombinant protein corresponding to the C-terminal region of the fascin molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: fascin actin-bundling protein 1
Light Chain: Kappa
Application Note: WB: 1:100–1:200. IHC-P: 1:200–1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 55
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Uniprot ID: Q16658
Antigen Species: Human
Immunogen: Prokaryotic recombinant protein corresponding to the C-terminal region of the fascin molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: fascin actin-bundling protein 1
| Artikelnummer | GTX01968-500 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX01968-500 |
| Green Labware | Nein |
| Verpackungseinheit | 500 μl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (paraffin), Western Blotting |
| Isotyp | IgG1 |
| Human Gene ID | 6624 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
