Fascin 1 antibody (ZM192)

Clone Name: ZM192

Light Chain: Kappa

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 55

Positive Control: Hodgkin's lymphoma or spleen

Form: Liquid

Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Uniprot ID: Q16658

Antigen Species: Human

Immunogen: Full length recombinant human FSCN1 protein

Purification: Purified IgG

Conjugation: Unconjugated

Full Name: fascin actin-bundling protein 1

• Artikelnummer: GTX01691-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX01691-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2a
• Human Gene ID: 6624
• Wirt: Mouse