Fc epsilon R1 alpha antibody (MAR-1) (PE)

Fc epsilon R1 alpha antibody (MAR-1) (PE)
Artikelnummer
GTX01480-08-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Clone Name: MAR-1

Product Description: The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo.

Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 30

Form: Liquid

Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]

Uniprot ID: P12319

Purification: Purified by affinity chromatography

Conjugation: PE

Full Name: Fc fragment of IgE receptor Ia
Mehr Informationen
Artikelnummer GTX01480-08-100
Hersteller GeneTex
Hersteller Artikelnummer GTX01480-08-100
Green Labware Nein
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Mouse (Murine)
Klonalität Monoclonal
Methode Flow Cytometry
Isotyp IgG
Human Gene ID 2205
Wirt Hamster
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