FcRn Complex (FCGRT/B2M), His-Avi-Tag, Biotin-Labeled, HiP™ Recombinant

Products from BPS Bioscience require a minimum order value above 400€

Applications: Useful for the study of FcRn and Fc interactions and binding kinetics.

Description: Human FcRn also known as neonatal Fc receptor is a heterodimer of FCGRT (Fc Fragment of IgG Receptor and Transporter) and B2M (beta 2 microglobulin), GenBank Accession numbers NM_001136019 and NM_004048; a.a. 24-297 and a.a. 1-119 respectively. FCGRT has a C-terminal His-Avi-tag. This protein is enzymatically biotinylated using AviTag™ technology. These proteins are co-expressed in a HEK293 expression system. MW = 48 kDa

Format: Aqueous buffer solution

Formulation: 40 mM MES pH 5.0, 120 mM NaCl and 20% glycerol.

Genbank: FcRn: NM_001136019, B2M: NM_004048

Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary use carrier protein (BSA 0.1 - 0.5%).

Tags: C-terminal His-Avi-tag

Uniprot: P55899 (FCGRT), P61769 (B2M)

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1.Roopenian, D., et al., Nature. 2007 Sep 7: 715-7252.Shields, R. et al., Biological Chemicstry. 2000 Nov; 276:6591-6604.

• Artikelnummer: BPS71283-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71283-1
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK