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FOXP3 antibody (MF23) (APC)
FOXP3 antibody (MF23) (APC)
Artikelnummer
GTX01488-07-100
Verpackungseinheit
100 μg
Hersteller
GeneTex
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Clone Name: MF23
Product Description: The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 47
Form: Liquid
Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Uniprot ID: Q99JB6
Purification: Purified by affinity chromatography
Conjugation: APC
Full Name: forkhead box P3
Product Description: The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 47
Form: Liquid
Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Uniprot ID: Q99JB6
Purification: Purified by affinity chromatography
Conjugation: APC
Full Name: forkhead box P3
| Artikelnummer | GTX01488-07-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX01488-07-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μg |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine) |
| Klonalität | Monoclonal |
| Methode | Flow Cytometry |
| Isotyp | IgG2b |
| Human Gene ID | 20371 |
| Wirt | Rat |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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