FUBP1 antibody (AT14F5)

Clone Name: AT14F5

Light Chain: Kappa

Calculated MW: 68

Form: Liquid

Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Uniprot ID: Q96AE4

Antigen Species: Human

Immunogen: The clone AT14F5 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FUBP3 protein.

Purification: Protein A Purified

Conjugation: Unconjugated

Full Name: far upstream element binding protein 1

• Artikelnummer: GTX57628-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX57628-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG2b
• Human Gene ID: 8880
• Wirt: Mouse