Garcinol, CAS 78824-30-3

HAT inhibitor

Product Type: Inhibitor

CAS No.: 78824-30-3

MolecularFormula: C38H50O6

Molecular Weight: 602,8

Source: Synthetic

Purity: >98% (TLC), NMR conforms

Solubility: Soluble in 25 mg/ml DMSO or 25 mg/ml Ethanol

Appearance: Yellow solid

PubChem CID: 5490884

Scientific Background: Potent inhibitor of histone acetyl transferases p300 (IC50=7 mM) and pCAF (IC50=5 mM) (1). Induces apoptosis in various cell lines (2). Promotes expansion of human hematopoietic stem cells(3). Cell permeable.

References: 1. Balasubramanyam K., et al., (2004) J. Biol. Chem. 279: 33716.2. Parasramka M.A., et al. (2011) Nutr. Cancer. 63: 456.3. Nishino T., et al. (2011) Nutr. PLoS One 6: e24298.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-355-25MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-355-25MG
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK