Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GBP2
Key Reference: Lukasiewicz,R., (2007) J. Biol. Chem. 282 (32), 23036-23043
Molecular Weight: 67kDa
Peptide Sequence: Synthetic peptide located within the following region:
HTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Interferon-induced guanylate-binding protein 2
Protein Size: 591
Purification: Affinity Purified