GITR (CD357), Fc Fusion, Biotin-labeled (Human) Recombinant

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Assay Conditions: GITR-biotin binding to GITRL was confirmed using the GITRL:GITR[Biotinylated] Inhibitor Screening Assay Kit (BPS Cat. #72061).

Description: Human secreted GITR, also known as Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, and CD357, GenBank Accession No. NM_004195, a.a. 26-161 expressed in a HEK293 cell expression system, fused at the C-terminus to the Fc portion of human IgG1, and enzymatically biotin-labeled using Avi-tag™ technology. MW = 43 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Format: Aqueous buffer solution

Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Genbank: NM_004195

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1)

Uniprot: Q9Y5U5

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1.Shimizu, J., et al., Nat. Immunol. 2002; 3: 135-142.2.Ko, K., et al., J. Exp. Med. 2005; 202(7): 885-891.

• Artikelnummer: BPS71256-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71256-1
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK