Glucokinase (GCK) Polyclonal Antibody, Rabbit

Abbreviation: Glucokinase (GCK)

Target Synonym: GCK;FGQTL3;GK;GLK;HHF3;HK4;HKIV;HXKP;LGLK;MODY2

Conjugation: Unconjugated

UNIProt ID: P35557

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human Glucokinase

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-93390-60
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93390-60
• Green Labware: Nein
• Verpackungseinheit: 60 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit