GluN2A/NR2A Antibody, Clone N327/95: ATTO 488

Mouse Anti-Rat GluN2A/NR2A Monoclonal IgG2A

Target: NMDAR2A NMDA

Conjugate: ATTO 488

Product Type: Monoclonal

Clone Number: N327/95 (Formerly sold as S327-95)

Immunogen: Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A

Swiss-Prot: Q00959

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~170kDa. Does not react with NR2B.

Cellular Localization: Cell Membrane,Cell Junction

Scientific Background: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D).

References: 1. Teng H.J., et al. (2010) PLoS ONE. 5: e13342.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-429D-A488
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-429D-A488
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2a
• Human Gene ID: 24409
• Wirt: Mouse