GluN2B/NR2B Antibody, Clone S59: PerCP

Mouse Anti-Rat GluN2B/NR2B Monoclonal IgG2b

Target: NR2B

Conjugate: PerCP

Product Type: Monoclonal

Clone Number: S59

Immunogen: Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B

Swiss-Prot: Q00960

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~166kDa. No cross-reactivity against NR2A.

Cellular Localization: Cell Membrane,Cell Junction,Synapse,Postsynaptic Cell Membrane

Scientific Background: NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (1). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (2).

References: 1. Zhuo M. (2009) Mol Brain. 2(1): 42. Gurwitz D, and Weizman A. (2002) Drug Discovery Today, 7(7): 403-406.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-337D-PCP
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-337D-PCP
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2b
• Human Gene ID: 24410
• Wirt: Mouse