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Encompassing Amino Acids: 1-345(end)
Application: Useful for for animal immunization and ELISA.
Background: G protein-coupled receptor class C group 5 member D (GPRC5D) is an orphan receptor of little-known function belonging to the large family of G protein-coupled receptors. The protein is highly expressed in malignant plasma cells such multiple myeloma and is now considered a therapeutic target for antibody-based treatment of multiple myeloma. For example, CAR T cells and GPCR5DxCD3 bispecific antibodies are under development.
Description: Human GPRC5D (G-protein coupled receptor family C group 5 member D) protein (VLP), full length encompassing amino acids 1-345(end). This construct contains a C-terminal His-tag (10xHis) and was produced using VLP (virus-like particle) technology.
Endotoxin Level: <1 EU/µg (determined by LAL method)
Format: Lyophilized powder.
Formulation: Lyophilized from a 0.2 µm filtered solution of PBS, 6% Trehalose, pH 7.4.
Purity: ≥80% (determined by SDS-PAGE)
Reconstitution: It is not recommended to reconstitute to a concentration less than 100 µg/mL in ddH2O.
Storage Stability: Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is
recommended to freeze aliquots at -20°C or -80°C for extended storage.
Tags: C-terminal His-tag
Uniprot: Q9NZD1-1
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: BSL-1
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