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GPS2 antibody (HL2276)
GPS2 antibody (HL2276)
Artikelnummer
GTX638329-S-25
Verpackungseinheit
25 μl
Hersteller
GeneTex
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Clone Name: HL2276
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 37
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]
Uniprot ID: Q13227
Antigen Species: Human
Immunogen: Recombinant fragmemt of human GPS2.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: G protein pathway suppressor 2
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 37
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]
Uniprot ID: Q13227
Antigen Species: Human
Immunogen: Recombinant fragmemt of human GPS2.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: G protein pathway suppressor 2
| Artikelnummer | GTX638329-S-25 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX638329-S-25 |
| Green Labware | Nein |
| Verpackungseinheit | 25 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus), Zebrafish |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry |
| Isotyp | IgG |
| Human Gene ID | 2874 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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