Product Type: Inhibitor
CAS No.: 349085-38-7
MolecularFormula: C18H21N5O3
Molecular Weight: 355,39
Source: Synthetic
Purity: >98%
Solubility: Soluble to 100 mM in DMSO
Appearance: White solid
PubChem CID: 1150897
Scientific Background: Selective TRPA1 channel blocker that antagonizes AITC-and formalin-evoked calcium influx. Doe not block currents mediated by TRPV1, V3, V4, hERG or Nav1.2 channels (1-2).
References: 1. McNamara C.R., et al. (2007) Proc Natl Acad Sci USA. 104(33): 13525-13530.2. Taylor-Clark T.E., et al. (2008) Mol Pharmacol. 73(2): 274-281.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.