Target Synonym: HDAC6;CPBHM;HD6;JM21;PPP1R90
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human HDAC6
Dilution: WB 1:500-1:2000
Calculated MW: 114kDa/131kDa
Observed MW: 170kDa