Clone Name: 15C2.C11.F2.G11
Light Chain: Kappa
Application Note: WB: 1 μg/mL. ELISA: 1:20,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 16
Specificity/Sensitivity: This antibody detect the E6K mutant in the hemoglobin beta subunit and does not react with the HbA, HbS, HbF, or HbA-2 isoforms.
Form: Liquid
Buffer (with preservative): 0.02 M Potassium phosphate, 0.15 M Sodium chloride pH 7.2, 0.01% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
Uniprot ID: P68871
Antigen Species: Human
Immunogen: Synthetic peptide corresponding to amino acid residues near the N-terminus of Hb β-subunit conjugated to KLH.
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: hemoglobin subunit beta