HLA-DPB1 Polyclonal Antibody, Rabbit

Abbreviation: HLA-DPB1

Target Synonym: DPB1;HLA-DP;HLA-DP1B;HLA-DPB;HLA-DPB1;major histocompatibility complex;class II;DP beta 1

Conjugation: Unconjugated

UNIProt ID: P04440

Background: HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human HLA-DPB1

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-93178-60
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93178-60
• Green Labware: Nein
• Verpackungseinheit: 60 µl
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit