HLA-Pan (MHC II)(rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL

HLA-Pan (MHC II)(rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL
Artikelnummer
BTMBNC743475-500
Verpackungseinheit
500 uL
Hersteller
Biotium

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Description: Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Product Origin: Animal

Clone: rHLA-Pan/3475

Immunogen: Non-T, non-B human acute lymphoblastic leukemia REH6 cells

Antibody Reactivity: HLA-Pan/MHCII

Entrez Gene ID: 3115; 3117; 3122

Z-Antibody Applications: Flow (verified)/IF (verified)/IHC, FFPE (verified)

Verified AB Applications: Flow (verified)/IF (verified)/IHC (FFPE) (verified)

Antibody Application Notes: For coating for ELISA, order Ab without BSA/Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Optimal dilution and staining procedure for a specific application should be determined by user/Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
Mehr Informationen
Artikelnummer BTMBNC743475-500
Hersteller Biotium
Hersteller Artikelnummer BNC743475-500
Verpackungseinheit 500 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Recombinant
Methode Immunofluorescence, Flow Cytometry, Immunohistochemistry
Isotyp IgG1 kappa
Wirt Mouse
Konjugat Conjugated, CF740
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