IL-1 beta, Canine

Product Description: IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions[1][2]. IL-1 beta Protein, Canine consists of 152 amino acids (A115-S266) and is expressed in E. coli.

Formula: 403974(Gene_ID)Q28292 (A115-S266)(Accession)

References: [1]Karina Zitta, et al. Interleukin-1beta regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells. Biochem Biophys Res Commun. 2010 Sep 3;399(4):542-7./[2]Kenichi Shimada, et al. Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One. 2011;6(6):e21477./[3]Jan Petrasek, et al. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest. 2012 Oct;122(10):3476-89.

Molecular Weight: Approximately 17 kDa

Compound Purity: 96.00

• Artikelnummer: MEXHY-P73146-100UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P73146-100UG
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK