IL-17RA, Fc fusion, Biotin-labeled (Human) Recombinant

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Encompassing Amino Acids: 33-320

Application: Useful for studying protein function and protein-protein interaction.

Assay Conditions: 100 ng of IL-17A (BPSCat. #91014) was coated onto a 96-wellplate overnight. The indicated amount of IL-17RA, Biotin was added in IL-17 AssayBuffer and allowed to incubate at roomtemperature for 2 hr. Strep-HRP was added,followed by chemiluminescent substrate anddetection.

Description: Human secreted interleukin17 receptor A (IL-17RA) Fc fusion protein,also known as, IL-17 receptor A andCD217, GenBank Accession No. NM_014339, a.a 33-320, fused at the C-terminusto the Fc portion of human IgG1 with a CterminalAviTag™, expressed in a HEK293cell expression system. The protein isenzymatically biotinylated using AviTag™technology. This protein runs at a higherM.W. by SDS-PAGE due to glycosylation.

Format: Aqueous buffer solution

Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol

Genbank: NM_ 014339

Host Cell Line: HEK293

Storage Stability: At least 6 months at -80°C.

Tags: Fc Fusion (Human IgG1)

Uniprot: Q96F46

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 g/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Iwakura Y, et al. Immunol Rev. 2008. 226:57-79.
2. Bullens DM, et al. Clin Dev Immunol. 2013. 2013:840315.

• Artikelnummer: BPS91013-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 91013-1
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK
• Wirt: Human